Неотложная медицинская помощь (Feb 2016)

ENDOGENOUS INTOxICATION AND SEPSIS

  • I. V. Aleksandrova,
  • S. B. Matveyev,
  • E. V. Klychnikova,
  • S. I. Rei,
  • E. V. Tazina,
  • M. A. Godkov

Journal volume & issue
Vol. 0, no. 1
pp. 20 – 23

Abstract

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RELEVANCE. Sepsis is always accompanied by endogenous intoxication (EI). It is very important to study EI in the patients with severe sepsis and septic shock.MATERIAL AND METHODS. Twenty seven patients with severe sepsis and thirteen with septic shock in the postoperative period were enrolled into the study. EI was assessed using the measurements of total and effective albumin concentrations (EAC), middle-molecular-weight proteins (MMWP) and EI index (Kei=MMWP/ EAC)x1000.RESULTS. The use of the EI index in patients with severe sepsis and septic shock leads to improvement of diagnostic and therapy monitoring.

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