Tritiated bile acids: problems and recommendations

D.K. Panveliwalla; D. Pertsemlidis; E.H. Ahrens, Jr.

doi:10.1016/s0022-2275(20)36775-4

Journal of Lipid Research (Sep 1974)

Tritiated bile acids: problems and recommendations

D.K. Panveliwalla,
D. Pertsemlidis,
E.H. Ahrens, Jr.

Affiliations

D.K. Panveliwalla: The Rockefeller University, New York 10021, and Mount Sinai School of Medicine, City University of New York, New York 10029; Mount Sinai School of Medicine, City University of New York, New York 10029
D. Pertsemlidis: The Rockefeller University, New York 10021, and Mount Sinai School of Medicine, City University of New York, New York 10029; Mount Sinai School of Medicine, City University of New York, New York 10029
E.H. Ahrens, Jr.: The Rockefeller University, New York 10021, and Mount Sinai School of Medicine, City University of New York, New York 10029; Mount Sinai School of Medicine, City University of New York, New York 10029

DOI: https://doi.org/10.1016/s0022-2275(20)36775-4
Journal volume & issue: Vol. 15, no. 5
pp. 530 – 532

Abstract

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Kinetic studies of cholic and chenodeoxycholic acids were carried out in three patients by simultaneous intravenous administration of appropriate pairs of 3H- and 14C-labeled compounds. The results obtained indicated two sources of error: chemical impurity and loss of tritium by biological exchange. Precautions are listed for use of tritiated bile acids in studies of pool sizes and turnover rates.

Published in Journal of Lipid Research

ISSN: 0022-2275 (Print); 1539-7262 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.journals.elsevier.com/journal-of-lipid-research

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Abstract

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