Modern possibilities of antihypertensive and lipid-lowering therapy in the treatment of comorbid patients with a very high risk of cardiovascular events

Abstract

Hypertension and dyslipidemia are key risk factors for cardiovascular disease. Despite the currently existing possibilities for the combined use of various classes of antihypertensive and lipid-lowering drugs, the problem of treating patients with a high risk of cardiovascular events has not lost its significance and its solution in a specific clinical situation often remains very difficult. The review analyzes current data on the efficacy and safety of the fixed-dose combination of lisinopril, amlodipine and rosuvastatin to solve the problem of a personalized approach in the treatment of comorbid patients with a high risk of car­diovascular events.

Keywords

• hypertension
• coronary artery disease
• dyslipidemia
• fixed-dose combination
• lisinopril
• amlodipine
• rosuvastatin
• polypill