Archives of Biological Sciences (Jan 2007)
Anti-genotoxic effect of aloe vera gelR on the mutagenic action of ethyl methanesulfonate
Abstract
The antimutagenic effect of aloe vera gelR was investigated using the Drosophila sex-linked recessive lethal test (or SLRL test). In this assay, 3-day-old adults were treated with a direct-acting mutagen - ethyl methanesulfonate (EMS), which was the positive control. The other group of individuals of the same age was firstly treated with EMS, and then with aloe vera gelR (co-treatment). When co-treatment experiments with aloe were carried out, it was effective in reducing genotoxicity of the direct-acting mutagen. .
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