Threshold Dynamics of an SIR Model with Nonlinear Incidence Rate and Age-Dependent Susceptibility

Abstract

We propose an SIR epidemic model with different susceptibilities and nonlinear incidence rate. First, we obtain the existence and uniqueness of the system and the regularity of the solution semiflow based on some assumptions for the parameters. Then, we calculate the basic reproduction number, which is the spectral radius of the next-generation operator. Second, we investigate the existence and local stability of the steady states. Finally, we construct suitable Lyapunov functionals to strictly prove the global stability of the system, which are determined by the basic reproduction number ℛ0 and some assumptions for the incidence rate.