Small Structures (Aug 2025)
Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
Abstract
Conductive hydrogels provide a flexible platform technology that enables the development of personalized materials for various neuronal diagnostic and therapeutic applications, combining the complementary properties of conductive materials and hydrogels. By ensuring conductivity through conductive materials, hydrogels largely compensate for the rigidity of traditional inorganic conductive materials, making them a suitable substitute. To adapt to different working environments, conductive hydrogels exhibit excellent properties, such as mechanical properties, adhesion, and biocompatibility, which further expand their applications. This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term stability and scalability of production.
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